Novel bicyclic hydroxamates as inhibitors of histone...

Details Novel bicyclic hydroxamates as inhibitors of histone... Novel bicyclic hydroxamates as inhibitors of histone...

C - Chemistry, Metallurgy

07

C

C07C 259/10 (2006.01) A61K 31/16 (2006.01) A61K 31/18 (2006.01) A61K 31/425 (2006.01) A61P 35/00 (2006.01) C07C 275/42 (2006.01) C07C 311/08 (2006.01) C07C 311/13 (2006.01) C07C 311/21 (2006.01) C07C 311/29 (2006.01) C07D 207/16 (2006.01) C07D 209/14 (2006.01) C07D 209/18 (2006.01) C07D 211/16 (2006.01) C07D 211/22 (2006.01) C07D 211/46 (2006.01) C07D 211/60 (2006.01) C07D 213/38 (2006.01) C07D 213/56 (2006.01) C07D 213/65 (2006.01) C07D 213/81 (2006.01) C07D 213/82 (2006.01) C07D 233/54 (2006.01) C07D 233/

Patent

CA 2473505

The present invention is directed to certain bicyclic hydroxamate derivatives that are inhibitors of histone deacetylase and are therefore useful in the treatment of diseases associated with histone deacetylase activity. Pharmaceutical compositions and processes for preparing these compounds are also disclosed

L'invention concerne certains dérivés d'hydroxamate bicyclique inhibiteurs de histone désacétylase et, par conséquent, utiles pour traiter des maladies associées à l'activité de histone désacétylase. Elle concerne également des compositions pharmaceutiques et des procédés servant à préparer ces composés.

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