Novel bisphosphonate derivatives, their preparation methods...

C - Chemistry – Metallurgy – 07 – F

Patent

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Details

C07F 9/40 (2006.01) A61K 31/663 (2006.01) A61P 19/08 (2006.01) A61P 35/00 (2006.01) C07F 9/38 (2006.01)

Patent

CA 2451881

The invention concerns novel salified or partly esterified 1-hydroxymethylene-1,1-bisphosphonic acid derivatives, pharmaceutical compositions comprising same, their therapeutic use, in particular for treating cancer tumours. The invention also concerns methods for preparing said derivatives.

La présente invention concerne de nouveaux dérivés salifiés ou partiellement estérifiés de l'acide 1-hydroxyméthylène-1, 1-bisphosphonique, des compositions pharmaceutiques les comprenant, leur application en thérapeutique, notamment pour le traitement des tumeurs cancéreuses. Elle a également trait à des procédés de préparations de ces dérivés.

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