Novel bombesin-related peptides

Details Novel bombesin-related peptides Novel bombesin-related peptides

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A61K 38/08 (2006.01) A61K 38/10 (2006.01) C07K 7/06 (2006.01) C07K 7/08 (2006.01) C07K 14/575 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2183556

A pure DNA encoding a peptide which encodes a novel bombesin-related peptide, i.e., H-pGlu-Gln-Ser-Leu-Gly-Asn-Gln-Trp-Ala-Arg-Gly-His-Phe-Met-NH2 or Gly- Asn-Gln-Trp-Ala-Arg-Gly-His-Phe-Met-NH2. Also disclosed are a vector and a cell containing such a DNA, a pharmaceutical composition which includes such a peptide, and a method of preparing such a peptide by recombinant technology.

On décrit un ADN pur qui code un peptide codant lui-même un nouveau peptide apparenté à la bombésine, à savoir H-pGlu-Gln-Ser-Leu-Gly-Asn-Gln-Trp-Ala-Arg-Gly-His-Phe-Met-NH¿2? ou Gly-Asn-Gln-Trp-Ala-Arg-Gly-His-Phe-Met-NH¿2?. On décrit aussi un vecteur et une cellule contenant un tel ADN, une composition pharmaceutique comprenant un tel peptide et un procédé qui permet de préparer ce peptide par génie génétique.

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