Novel c-3 s/o- and s/n formaldehe acetal derivatives of...

Details Novel c-3 s/o- and s/n formaldehe acetal derivatives of... Novel c-3 s/o- and s/n formaldehe acetal derivatives of...

C - Chemistry, Metallurgy

07

D

C07D 501/00 (2006.01) A61K 31/545 (2006.01) A61P 31/00 (2006.01) C07D 501/59 (2006.01)

Patent

CA 2461577

The compounds of the general formula (I) wherein R1 denotes a pharmaceutically acceptable side chain radical as used conventionally in the field of cephalosporins and wherein R2 denotes a pharmaceutically acceptable group which is bonded to the remaining part of the molecule by an oxygen-carbon single bond or a nitrogen-carbon single bond, and their pharmaceutically acceptable salts, esters and amide derivatives are effective antibiotics.

L'invention concerne des composés représentés par la formule générale (I), dans laquelle R<sp>1</sp> représente un radical à chaîne latérale acceptable sur le plan pharmaceutique tels que ceux utilisés traditionnellement dans le domaine des céphalosporines et R<sp>2</sp> représente un groupe acceptable sur le plan pharmaceutique lié à la partie restante de la molécule par une liaison simple oxygène-carbone ou azote-carbone. L'invention concerne enfin leurs sels, esters et dérivés amides acceptables sur le plan pharmaceutique qui sont efficaces en tant qu'antibiotiques.

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