Novel caffeic acid derivative, oraposide, and cosmetic or...

C - Chemistry – Metallurgy – 07 – H

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C07H 13/04 (2006.01) A61K 31/70 (2006.01) C07H 15/04 (2006.01) C07H 15/18 (2006.01)

Patent

CA 2102689

A novel derivative of caffeic acid has formula (I) where one or several R independently represent a hydrogen atom, a C1-C5 alkyl group, particularly methyl, an acyl group, particularly C1-C6, specifically acetyl. This novel derivative designated oraposide is particularly useful for preparing cosmetic or pharmaceutical, particularly dermatological, compositions due particularly to its activity against free radicals, inflammation and actinic ageing.

2102689 9216544 PCTABS00160 L'invention concerne un nouveau dérivé de l'acide caféique. Ce nouveau dérivé présente la formule (I) dans laquelle un ou plusieurs R représentent indépendamment un atome d'hydrogène, un groupe alkyle en C1-C5, en particulier méthyle, un groupe acyle, en particulier en C1-C6, notamment acétyle. Ce nouveau dérivé dénommé oraposide est particulièrement utile pour la préparation de compositions cosmétiques ou pharmaceutiques, notamment dermatologiques, grâce en particulier à une activité antiradicaux libres, anti-inflammatoires et anti-vieillissement actinique.

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