Novel calcium channels and uses thereof

Details Novel calcium channels and uses thereof Novel calcium channels and uses thereof

C - Chemistry, Metallurgy

07

K

C07K 14/705 (2006.01)

Patent

CA 2526841

Differentially expressed L-type calcium channel nucleic acid sequences and polypeptides have been identified that include novel sequences that are differentially expressed in non-excitable cells. Such sequences can be used, for example, as targets for identifying agents that modulate calcium influx, e.g., in non-excitable cells. Methods related to modulation of cell growth are also included.

La présente invention a trait à des séquences d'acides nucléiques et des polypeptides d'expression différentielle de canaux calciques de type L comportant de nouvelles séquences qui sont d'expression différentielle dans des cellules non excitables. De telles séquences peuvent être utilisées, par exemple, comme cibles pour l'identification d'agents de modulation de l'influx calcique, par exemple dans des cellules non excitables. L'invention a également trait à des procédés associés à la modulation de la croissance cellulaire.

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