Novel carbapenem compounds

C - Chemistry – Metallurgy – 07 – D

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C07D 477/14 (2006.01) A61K 31/407 (2006.01) A61P 31/04 (2006.01)

Patent

CA 2519794

Carbapenem compounds represented by the general formula [1] or pharmaceutically acceptable salts thereof: [1] wherein R1 is C1-3 alkyl or hydroxylated C1-3 alkyl; R is hydrogen or a group which is hydrolyzed in vivo into a carboxyl group; and G is a group represented by one of the general formulae [G1], [G2] and [G3].

L'invention concerne des composés de carbapenem représentés par la formule générale (I) ou leurs sels pharmaceutiquement compatibles. Dans la formule (I), R?1¿ représente alkyle C1-3 ou alkyle C1-3 hydroxylé ; R représente un hydrogène ou un groupe qui est hydrolysé in vivo en un groupe carboxyle ; et G représente un groupe d'une des formules générales suivantes : (G1) (G2) ou (G3).

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