C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 519/06 (2006.01) A61K 31/425 (2006.01) C07D 477/14 (2006.01) C07D 519/00 (2006.01)
Patent
CA 2189995
Novel carbapenem derivatives, represented by the following formula (I), having a substituted or unsubstituted imidazo[5,1-b]thiazolium-6-ylmethyl group at the 2-position are disclosed. The compounds represented by the formula (I) have potent antibacterial activity against a wide spectrum of bacteria from Gram-positive bacteria to Gram-negative bacteria including Pseudomonas aeruginosa and, in addition, have potent antibacterial activity against various .beta.-lactamase-producing bacteria and MRSA and are very stable against DHP-1. (see formula I)
Nouveaux dérivés de carbapénème représentés par la formule générale (I), et comprenant un groupe imidazo[5,1-b]thiazolium-6-yméthyle éventuellement substitué en position 2. Les composés selon l'invention ont une activité antibactérienne puissante et étendue sur les bactéries à gram positif et à gram négatif, dont pseudomonas aeruginosa, et ont un effet antibactérien puissant sur diverses bactéries produisant de la beta -lactamase et MRSA, ainsi qu'une stabilité DHP-1 extrêmement élevée.
Aihara Kazuhiro
Atsumi Kunio
Ishii Miyuki
Iwamatsu Katsuyoshi
Kano Yuko
Fetherstonhaugh & Co.
Meiji Seika Kabushiki Kaisha
LandOfFree
Novel carbapenem derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Novel carbapenem derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Novel carbapenem derivatives will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1677633