Novel cationic cholesteryl derivatives containing cyclic...

Details Novel cationic cholesteryl derivatives containing cyclic... Novel cationic cholesteryl derivatives containing cyclic...

C - Chemistry, Metallurgy

12

N

C12N 15/88 (2006.01) A61K 31/58 (2006.01) A61K 31/70 (2006.01) A61K 47/28 (2006.01) A61K 48/00 (2006.01) C07J 43/00 (2006.01) C12N 15/85 (2006.01) A61K 9/127 (2006.01)

Patent

CA 2251543

The present invention discloses compounds which are cationic cholesteryl derivatives having a nitrogen-containing ring structure as their polar head group. These compounds are useful for delivering biologically active substances to cells and for transfecting nucleic acids into cells.

L'invention porte sur des composés qui sont des dérivés de cholestéryle cationiques avec une tête polaire formée par une structure cyclique contenant de l'azote. Ces composés sont utiles pour délivrer des substances biologiquement actives et transfecter des acides nucléiques dans des cellules.

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