C - Chemistry – Metallurgy – 07 – H
Patent
C - Chemistry, Metallurgy
07
H
C07H 19/01 (2006.01) A61K 31/70 (2006.01) C07D 493/08 (2006.01)
Patent
CA 2109523
2109523 9220336 PCTABScor01 Disclosed herein are compounds of structural formula (I) which are useful as cholesterol lowering agents. These compounds are also useful as inhibitors of squalene synthetase, inhibitors of fungal growth, inhibitors of farnesyl-protein transferase and farnesylation of the oncogene protein Ras. These compounds are also useful in the treatment of cancer.
Acton John J. III
Berger Gregory D.
Bergstrom James D.
Biftu Tesfaye
Bugianesi Robert L.
Merck & Co. Inc.
Swabey Ogilvy Renault
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