C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 5/06 (2006.01) C07K 5/065 (2006.01) G01N 33/68 (2006.01)
Patent
CA 2450194
The invention relates to chromogenic compounds and the use thereof for the determination of enzymes of the family of carboxypeptidases N and carboxypeptidases U. The above is more specifically a compound of formula (I) in which A = (1), (2), (3), (4) or (5), R1, R2 = H, -CH¿3?, -CH(CH¿3?)¿2?, -OCH¿3?, -CI,-CF¿3?,-OCF¿3?,-SCH¿3?, R¿3? = an amino acid group which may be hydrolysed by a carboxypeptidase A and R¿4? = a basic amino acid group.
La présente invention est relative à des composés chromogènes et leur utilisation pour le dosage d'enzymes de la famille des carboxypeptidases N, et des carboxypeptidases U. Elle vise plus spécifiquement un composé de formule (I) dans laquelle A = (1) ou (2) ou (3) ou (4) ou (5), R1, R2 = H, -CH3, - CH(CH3)2, -OCH3, -CI,-CF3,-OCF3,-SCH3, R3 = un radical d'acide aminé hydrolysable par une carboxypeptidase A. R4 = un radical d'acide aminé basique.
Fetherstonhaugh & Co.
Societe Diagnostica-Stago
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