C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 233/22 (2006.01) A61K 31/415 (2006.01) A61K 31/454 (2006.01) A61K 31/496 (2006.01) A61K 31/5377 (2006.01) C07D 401/14 (2006.01) C07D 403/06 (2006.01)
Patent
CA 2569598
The present invention relates to compounds of the formula (I), and the pharmaceutically acceptable salts and esters thereof, a process for their manufacture, medicaments containing them as well as the use of these compounds as pharmaceutically active agents. The compounds show antiproliferative activity and may be especially useful for the treatment of cancer.
L'invention concerne des composés de formule (I), des sels et des esters de ceux-ci, acceptables au plan pharmaceutique, leur procédé de fabrication, des médicaments les contenant ainsi que l'utilisation de ces composés en tant qu'agents actifs au plan pharmaceutique. Ces composés possèdent une activité anti-prolifératifs et peuvent être particulièrement utiles pour le traitement du cancer.
Haley Gregory Jay
Kong Norman
Liu Emily Aijun
Vu Binh Thanh
F. Hoffmann-La Roche Ag
Gowling Lafleur Henderson Llp
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