Novel class of nucleic acid cationic transfecting agents

Details Novel class of nucleic acid cationic transfecting agents Novel class of nucleic acid cationic transfecting agents

C - Chemistry, Metallurgy

07

H

C07H 15/18 (2006.01) A61K 9/127 (2006.01) A61K 48/00 (2006.01) C07H 15/04 (2006.01) C12N 15/87 (2006.01) C12N 15/88 (2006.01)

Patent

CA 2292837

The invention concerns a novel class of nucleic acid cationic transfecting agents, characterised in that the transfecting agents comprise at least a lipophilic region associated with a cationic hydrophilic region, said cationic hydrophilic region consisting of a heterocycle with 5 or 6 atoms substituted by amino groups.

La présente invention concerne une nouvelle classe d'agents trans fectants cationiques des acides nucléiques, caractérisée en ce que les agents transfectants comprennent au moins une région lipophile associée à une région hydrophile cationique, ladite région hydrophile cationique étant constituée d'un hétérocycle à 5 ou 6 atomes substitué par des groupements aminés.

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