Novel composition containing an acid-labile omeprazole and...

A - Human Necessities – 61 – K

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Details

A61K 31/44 (2006.01) A61K 9/28 (2006.01) A61K 9/48 (2006.01) A61K 9/50 (2006.01) A61K 31/4184 (2006.01) A61K 31/4439 (2006.01)

Patent

CA 2231223

A composition, particularly adapted for oral administration, comprising omeprazole and a method for preparing it are provided, the composition being exempt of alkaline-reacting compounds and comprising a core constituted of nuclei and said benzimidazole, the nuclei and benzimidazole being compressed together, an intermediate layer and an enteric layer.

La présente invention concerne une composition convenant particulièrement à l'administration orale et comprenant un oméprazole. L'invention concerne également le procédé de préparation correspondant. Cette composition, exempte de composés réagissant aux alcalins, est constituée d'un noyau comprenant un nucléus et le benzimidazole considéré, le nucléus et le benzimidazole étant comprimés ensemble, d'un enrobage intermédiaire et d'un enrobage gastro-résistant.

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