A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/04 (2006.01) A61P 31/06 (2006.01) A61P 37/04 (2006.01) C07K 14/35 (2006.01) G01N 33/50 (2006.01) C12N 15/31 (2006.01)
Patent
CA 2731499
The present invention is directed to a polypeptide which comprises (i) an Rv3616c protein sequence, (11) a variant of an Rv3616c protein sequence, or (111) an immunogenic fragment of an Rv3616c protein sequence for use in the treatment or prevention of latent TB In other aspects the invention is directed to associated polynucleotides, fusion proteins and methods for the treatment or prevention of latent tuberculosis
La présente invention concerne un polypeptide qui comprend : (i) une séquence de protéine Rv3616c; (ii) une variante dune séquence de protéine Rv3616c; ou (iii) un fragment immunogène dune séquence de protéine Rv3616c pour une utilisation dans le traitement ou la prévention de la TB latente. Selon dautres aspects, linvention concerne des polynucléotides associés, des protéines de fusion et des procédés de traitement ou de prévention de la tuberculose latente.
Brown James
Mettens Pascal
Murphy Dennis
Glaxo Group Limited
Glaxosmithkline Biologicals S.a.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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