A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/04 (2006.01) C07K 14/35 (2006.01) G01N 33/569 (2006.01)
Patent
CA 2731549
The present invention is directed to a polypeptide which comprises: (i) an Rv1753c protein sequence; (ii) a variant of an Rv1753c protein sequence; or (iii) an immunogenic fragment of an Rv1753c protein sequence. In other aspects the invention is directed to associated polynucleotides, fusion proteins and methods for the treatment or prevention of tuberculosis.
La présente invention concerne un polypeptide qui comprend : (i) une séquence de la protéine Rv1753c ; (ii) un variant dune séquence de la protéine Rv1753c ; ou (iii) un fragment immunogénique dune séquence de la protéine Rv1753c. Dans dautres aspects, linvention concerne des polynucléotides associés, des protéines de fusion et des procédés pour le traitement ou la prévention de la tuberculose.
Brown James
Mettens Pascal
Murphy Dennis
Glaxo Group Limited
Glaxosmithkline Biologicals S.a.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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