Novel compositions and methods for treatment of diseases...

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 417/06 (2006.01) A61K 31/5415 (2006.01) A61P 11/06 (2006.01) A61P 29/00 (2006.01)

Patent

CA 2662215

The present invention relates to inhibiting proliferation and inducing apoptosis in activated lymphocytes, including T cells and B cells. The invention also provides compositions and methods for inhibiting proliferation and inducing apoptosis in activated lymphocytes, as well methods for treating diseases associated with activated lymphocytes by administering 5-HT receptor antagonists.

La présente invention concerne l'inhibition de la prolifération et l'induction de l'apoptose dans des lymphocytes activés, notamment des lymphocytes T et des lymphocytes B. L'invention concerne également des compositions et des procédés pour inhiber la prolifération et induire l'apoptose dans des lymphocytes activés, ainsi que des procédés de traitement de maladies associées avec des lymphocytes activés par administration d'antagonistes du récepteur 5-HT.

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