Novel compositions and methods in cancer

C - Chemistry – Metallurgy – 07 – H

Patent

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C07H 21/04 (2006.01)

Patent

CA 2563367

The present invention relates to novel sequences for use in detection, diagnosis and treatment of cancers, especially lymphomas. The invention provides cancer ~associated (CA) polynucleotide sequences whose expression is associated with cancer. The present invention provides CA polypeptides associated with cancer that presents novel therapeutic targets against cancer. The present invention further provides diagnostic compositions and methods for the detection of cancer. The present invention provides monoclonal and polyclonal antibodies specific for the CA polypeptides. The present invention also provides diagnostic tools and therapeutic compositions and methods for screening prevention and treatment of cancer.

La présente invention a trait à de nouvelles séquences destinées à être utilisées dans la détection, le diagnostic et le traitement de cancers, notamment des lymphomes. L'invention a trait à des séquences de polynucléotides associées au cancer dont l'expression est associée au cancer. La présente invention a également trait à des polypeptides associés au cancer qui présentent de nouveaux cibles thérapeutiques contre le cancer. La présente invention a trait en outre à des compositions et à des procédés diagnostiques pour la détection du cancer. La présente invention a également trait à des anticorps monoclonaux et polyclonaux spécifiques pour les polypeptides associés au cancer. Enfin, la présente invention a trait à des outils de diagnostic et des compositions et des procédés thérapeutiques pour le dépistage, la prévention et le traitement du cancer.

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