C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) A61K 38/17 (2006.01) A61K 39/395 (2006.01) A61K 47/48 (2006.01) A61K 48/00 (2006.01) C07H 21/00 (2006.01) C07K 14/47 (2006.01) C07K 16/00 (2006.01) C07K 16/18 (2006.01) C07K 16/30 (2006.01) C12P 21/08 (2006.01) C12Q 1/00 (2006.01) C12Q 1/68 (2006.01) C40B 40/08 (2006.01) G01N 33/574 (2006.01)
Patent
CA 2508944
The present invention relates to novel sequences for use in detection, diagnosis and treatment of cancers, especially lymphomas. The invention provides cancer-associated (CA) polynucleotide sequences whose expression is associated with cancer. The present invention provides CA polypeptides associated with cancer and provides diagnostic compositions and methods for the detection of cancer. The present invention provides monoclonal and polyclonal antibodies specific for the CA polypeptides. The present invention also provides diagnostic tools and therapeutic compositions and methods for screening, prevention and treatment of cancer.
L'invention concerne de nouvelles séquences à utiliser pour détecter, diagnostiquer et traiter le cancer, notamment les lymphomes. L'invention concerne des séquences polynucléotidiques associées au cancer, dont l'expression est associée au cancer. L'invention concerne également des polypeptides associés au cancer ainsi que des compositions et procédés de diagnostic permettant de détecter le cancer. Elle concerne en outre des anticorps monoclonaux et polyclonaux spécifiques pour ces polypeptides associés au cancer. Elle concerne enfin des outils de diagnostic et des compositions thérapeutiques, ainsi que des procédés de criblage, de prévention et de traitement du cancer.
Malandro Marc S.
Morris David W.
Borden Ladner Gervais Llp
Sagres Discovery Inc.
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