Novel compositions and methods in cancer

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/12 (2006.01) A61K 45/00 (2006.01) A61P 35/00 (2006.01) C07K 14/82 (2006.01) C07K 16/32 (2006.01) C07K 17/00 (2006.01) C12Q 1/68 (2006.01) G01N 33/50 (2006.01) G01N 33/574 (2006.01)

Patent

CA 2511817

The present invention relates to novel sequences for use in detection, diagnosis and treatment of cancers. The invention provides cancer-associated (CA) polynucleotide sequences whose expression is associated with cancer. The present invention provides CA polypeptides associated with cancer and provides diagnostic compositions and methods for the detection of cancer. The present invention provides monoclonal and polyclonal antibodies specific for the CA polypeptides. The present invention also provides diagnostic tools and therapeutic compositions and methods for screening, prevention and treatment of cancer.

L'invention concerne des séquences pour la détection, le diagnostic et le traitement du cancer. Il s'agit de séquences polynucléotidiques associées au cancer, dont l'expression est associée au cancer. On décrit des polypeptides associés au cancer, ainsi que des compositions et des procédés pour la détection du cancer. L'invention concerne des anticorps monoclonaux et polyclonaux spécifiques à ces polypeptides. L'invention concerne également des outils diagnostiques ainsi que des compositions thérapeutiques et des procédés pour la détection, la prévention et le traitement du cancer.

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