C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) C07K 14/435 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) G01N 33/50 (2006.01)
Patent
CA 2348733
Described heron are proteins useful in T-cell and B-cell activation. In particular, a human SWAP70 homolog found in a T-cell library and a human RasGRP homolog are described. Also described is the binding of RasGRP to SWAP70 and the human homolog
L'invention concerne des protéines pouvant être utilisées dans l'activation des lymphocytes T et des lymphocytes B, et plus particulièrement un homologue SWAP 70 humain découvert dans une bibliothèque de lymphocytes T, ainsi qu'un homologue RasGRP humain. Cette invention concerne également la liaison de RasGRP à SWAP70 et son homologue humain, ci-après dénommé JEST. Cette invention concerne enfin des procédés permettant d'identifier des modulateurs des protéines susmentionnées, ainsi que leurs interactions.
Rigel Pharmaceuticals Inc.
Smart & Biggar
LandOfFree
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