Novel compositions based on a synergistic combination of one...

Details Novel compositions based on a synergistic combination of one... Novel compositions based on a synergistic combination of one...

A - Human Necessities

61

K

A61K 31/59 (2006.01) A61P 17/06 (2006.01)

Patent

CA 2204437

A novel combination of one or more ligands with VDR receptor selective activity and one or more retinoids selective for RAR.gamma. receptors as opposed to RAR.alpha. receptors is described, as well as the use thereof in cosmetic and skin-care applications for treating disorders related to a hyperproliferation of cells, in particular skin cells, such as psoriasis.

L'invention concerne une nouvelle association à base d'au moins un ligand présentant une activité sélective pour le récepteur VDR et d'un rétinoïde sélectif des récepteurs RAR.gamma. par rapport aux récepteurs RAR.alpha., l'utilisation en dermatologie ou en cosmétique de cette association, destinée à traiter les désordres liés à une hyperprolifération cellulaire, plus particulièrement de cellules de la peau, telles que le psoriasis.

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