Novel compositions for treatment of diseases related to...

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 417/06 (2006.01) A61K 31/5415 (2006.01) A61P 37/00 (2006.01) C07D 279/28 (2006.01)

Patent

CA 2716396

The present invention relates to inhibiting proliferation and inducing apoptosis in activated lymphocytes, including T cells and B cells. The invention also provides compositions and methods for inhibiting proliferation and inducing apoptosis in activated lymphocytes, as well methods for treating diseases associated with activated lymphocytes by administering 5-HT receptor antagonists.

Cette invention concerne linhibition de la prolifération et linduction de lapoptose chez des lymphocytes activés, lymphocytes T et lymphocytes B y compris. Linvention concerne également des compositions et des méthodes dinhibition de la prolifération et dinduction de lapoptose chez des lymphocytes activés, ainsi que des méthodes de traitement des maladies associées avec des lymphocytes activés en administrant des antagonistes des récepteurs 5-HT.

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