Novel compositions which inhibit melanogenesis and uses thereof

Details Novel compositions which inhibit melanogenesis and uses thereof Novel compositions which inhibit melanogenesis and uses thereof

A - Human Necessities

61

K

A61K 8/60 (2006.01) A61K 8/73 (2006.01) A61K 31/7088 (2006.01) A61K 31/7105 (2006.01) A61P 17/00 (2006.01) A61Q 19/02 (2006.01) C12N 15/11 (2006.01)

Patent

CA 2720664

The present invention relates to novel pharmaceutical or cosmetic compositions comprising at least one inhibitor of a subunit of the AP-1 adaptor complex, of a kinesin which interacts with AP-1, in particular Kif13A, or of the interaction between a subunit of the AP-1 adaptor complex and said kinesin, and also to the use thereof for the manufacture of a medicament for use in the treatment of pigmentary disorders and as a depigmenting agent.

La présente invention concerne de nouvelles compositions pharmaceutiques ou cosmétiques comprenant au moins un inhibiteur d'une sous-unité du complexe adaptateur AP-1, d'une kinésine interagissant avec AP-1, en particulier Kif13A, ou de l'interaction entre une sous-unité du complexe adaptateur AP-1 et ladite kinésine, ainsi que leur utilisation pour la fabrication d'un médicament destiné au traitement de troubles pigmentaire et comme agent dépigmentant.

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