Novel compound...

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 16/44 (2006.01) C07D 405/04 (2006.01) C07H 19/044 (2006.01) C12N 5/12 (2006.01) C12Q 1/00 (2006.01) G01N 33/50 (2006.01) G01N 33/53 (2006.01)

Patent

CA 2300913

The present invention relates to a method for testing a biological function by quantitating 2-amino-3-[2-(.alpha.-mannopyranosyl)indole-3-yl]propionic acid in a collected biological sample and determining the biological function based on the quantitated values; to an antibody specifically reactive with 2-amino-3-[2-(.alpha.-mannopyranosyl)indole-3-yl]propionic acid; to a hybridoma that produces the antibody; and to a method for immunologically quantitating 2-amino-3-[2-(.alpha.-mannopyranosyl)indole-3-yl]propionic acid in a sample by using the antibody.

Nouveau composé <u>in vivo</u> d'acide 2-amino-3-[2-( alpha -mannopyranosyl)indol-3-yl]propionique; procédé servant à vérifier le fonctionner d'un corps vivant et consistant à déterminer la quantité d'acide 2-amino-3-[2-( alpha -mannopyranosyl)indol-3-yl]propionique dans un spécimen prélevé de ce corps vivant et à évaluer le fonctionnement de ce corps vivant à partir de la valeur déterminée; anticorps réagissant de façon spécifique avec acide 2-amino-3-[2-( alpha -mannopyranosyl)indol-3-yl]propionique; hybridome produisant cet anticorps; procédé servant à effectuer le dosage immunologique d'acide 2-amino-3-[2-( alpha -mannopyranosyl)indol-3-yl]propionique dans un spécimen au moyen de l'anticorps; procédé servant à préparer des dérivés d'acide 2-amino-3-[2-( alpha -mannopyranosyl)indol-3-yl]propionique.

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