Novel compounds 010

Details Novel compounds 010 Novel compounds 010

C - Chemistry, Metallurgy

07

D

C07D 205/04 (2006.01) A61K 31/4015 (2006.01) A61K 31/45 (2006.01) A61P 11/06 (2006.01) A61P 11/08 (2006.01) A61P 37/08 (2006.01) C07D 207/16 (2006.01) C07D 211/60 (2006.01) C07D 401/12 (2006.01) C07D 407/12 (2006.01) C07D 409/12 (2006.01) C07D 413/12 (2006.01) C07D 417/12 (2006.01)

Patent

CA 2706679

The present invention provides compounds of formula (I) in which n, y, X1, X2, A, B, R1, R2, R3, R4 and R5 are as defined in the specification, a process for their preparation, pharmaceutical compositions containing them and their use as dipeptidyl peptidase I (DPPI) inhibitors.

L'invention concerne des composés de formule (I) : (I), dans laquelle n, y, X1, X2, A, B, R1, R2, R3, R4 et R5 sont tels que définis dans la description. L'invention concerne également un procédé de préparation associé, des compositions pharmaceutiques les contenant, ainsi que leur utilisation en tant qu'inhibiteurs de la dipeptidylpeptidase I (DPPI).

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