Novel compounds

Details Novel compounds Novel compounds

C - Chemistry, Metallurgy

12

N

C12N 15/16 (2006.01) A61K 31/70 (2006.01) A61K 38/00 (2006.01) A61K 38/22 (2006.01) A61K 39/395 (2006.01) A61K 45/00 (2006.01) A61K 48/00 (2006.01) C07K 14/48 (2006.01) C07K 14/575 (2006.01) C07K 16/22 (2006.01) C07K 16/26 (2006.01) C12N 15/09 (2006.01) C12P 21/02 (2006.01) C12Q 1/68 (2006.01) G01N 33/50 (2006.01) G01N 33/53 (2006.01) G01N 33/74 (2006.01)

Patent

CA 2236489

HPMBQ91 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing HPMBQ91 polypeptides and polynucleotides in the design of protocols for the treatment of neuronal disorders including pain, CNS related disorders, gastrointestinal disorders, cardiovascular disorders, metabolic disorders including diabetes and obesity, smooth muscle disorders, inflammatory disorders including asthma, cancers including adenomas, leiomyomas, liposarcomas, lipomas, melanomas, pulmonary chondroid hamartomas, lung cancer, prostate cancer and breast cancer, among others, and diagnostic assays for such conditions.

Divulgation de polypeptides et de polynucléotides HPMBQ91, ainsi que de méthodes de production de tels polypeptides par des techniques de recombinaison. Des méthodes pour utiliser les polypeptides et les polynucléotides HPMBQ91 dans la conception de protocoles pour le traitement de troubles neuronaux, dont la douleur, des troubles liés au SNC, des troubles gastro-intestinaux, des troubles cardio-vasculaires, des troubles du métabolisme comme le diabète et l'obésité, des troubles des muscles lisses, des troubles inflammatoires comprenant l'asthme, des cancers, tels les adénomes, les léiomyomes, les liposarcomes, les lipomes, les mélanomes, les hamartomes chondroïdes pulmonaires, le cancer du poumon, le cancer de la prostate et le cancer du sein, entre autres, de même que des épreuves diagnostiques pour de telles conditions sont dévoilées.

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