C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) A61K 31/70 (2006.01) A61K 38/17 (2006.01) A61K 48/00 (2006.01) C07K 14/705 (2006.01) C07K 16/28 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01) G01N 33/68 (2006.01)
Patent
CA 2247800
hKv4.3 potassium channel family polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing hKv4.3 polypeptides and polynucleotides in the design of protocols for the treatment of cardiac arrhythmias and Alzheimer's disease, among others, and diagnostic assays for such conditions.
L'invention porte sur des polypeptides et des polynucléotides de la famille des canaux de potassium hKv4.3 et sur les procédés de production de ces polypeptides à l'aide de techniques de recombinaison. L'invention porte également sur des procédés d'utilisation des polynucléotides et polypeptides hKv4.3 pour la conception de protocoles utilisés dans le traitement des arythmies cardiaques et de la maladie d'Alzheimer, entre autres, et dans les tests diagnostiques de ces pathologies.
Bril Antoine Michel Alain
Calmels Thierry Paul Gerard
Faivre Jean-Francois Simon Pierre
Javre Jean-Luc
Rouanet Sabine
Gowling Lafleur Henderson Llp
Smithkline Beecham Laboratoires Pharmaceutiques
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