Novel compounds and compositions as protease inhibitors

C - Chemistry – Metallurgy – 07 – C

Patent

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C07C 271/22 (2006.01) A61K 31/275 (2006.01) A61K 31/395 (2006.01) A61P 11/00 (2006.01) A61P 17/00 (2006.01) A61P 25/00 (2006.01) A61P 29/00 (2006.01) A61P 33/00 (2006.01) A61P 35/00 (2006.01) A61P 37/00 (2006.01) C07C 255/29 (2006.01) C07C 255/60 (2006.01) C07C 311/06 (2006.01) C07C 311/09 (2006.01) C07C 317/50 (2006.01) C07C 323/60 (2006.01) C07C 323/62 (2006.01) C07D 207/14 (2006.01) C07D 207/16 (2006.01) C07D 209/06 (2006.01) C07D 209/26 (2006.01) C07D 209/52 (2006.01) C07D 211/58 (2006.01) C07D 211/60 (

Patent

CA 2368148

The present invention relates to novel N-cyanomethyl amides which are cysteine protease inhibitors, the pharmaceutically acceptable salts and N-oxides thereof, their uses as therapeutic agents and the methods of their making.

La présente invention a trait à de nouveaux amides N-cyanométhyle qui constituent des inhibiteurs de cystéine protéase, à leurs sels et à leurs N-oxydes pharmaceutiquement acceptables, à leur utilisation comme agents thérapeutiques et à leurs procédés de fabrication.

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