C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 225/06 (2006.01) A61K 31/395 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2669047
The present invention relates to ansamycin analogues that are useful, e.g. in the treatment of cancer, B-cell malignancies, malaria, fungal infection, diseases of the central nervous system and neurodegenerative diseases, diseases dependent on angiogenesis, autoimmune diseases or a prophylactic pretreatment for cancer. The present invention also provides methods for the production of these compounds and their use in medicine.
La présente invention concerne des analogues d'ansamycine trouvant une utilité, par exemple, dans le traitement du cancer, de tumeurs malignes des lymphocytes B, de la malaria, d'une infection fongique, de maladies du système nerveux central et de maladies neurodégénératives, de maladies dépendant de l'angiogenèse ou de maladies auto-immunes, ou dans le traitement préventif du cancer. La présente invention concerne également des procédés de production de ces composés ainsi que leur utilisation en médecine.
Biotica Technology Limited
Bristol-Myers Squibb Company
Gowling Lafleur Henderson Llp
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