C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 285/24 (2006.01) A61K 31/18 (2006.01) A61K 31/505 (2006.01) A61K 31/535 (2006.01) A61K 31/54 (2006.01) C07C 311/39 (2006.01) C07D 239/74 (2006.01) C07D 239/88 (2006.01) C07D 239/90 (2006.01) C07D 239/91 (2006.01) C07D 265/22 (2006.01) C07D 285/28 (2006.01) C07D 285/32 (2006.01) C07D 401/04 (2006.01) C07D 403/04 (2006.01) C07D 405/04 (2006.01) C07D 409/04 (2006.01) C07D 413/04 (2006.01) C07D 417/04 (2006.01) C07D 513/04 (2006.01)
Patent
CA 2320354
The invention provides novel compounds represented by general formula (I) wherein the bond represented by the broken line may be a single, double bond or absent; and if the bond is absent, then the nitrogen is substituted with a hydrogen and R2; X represents SO2 or C=O of CH2; Y represents -CH(R4)-, -N(R4)- or -N(R4)-CH2-, O; and the meaning of R2, R3, R4, R5, R6, R7, and R8 are as defined in the application. The compounds are useful as positive modulators of the AMPA-receptor.
La présente invention concerne de nouveaux composés représentés par la formule générale (I) où la liaison représentée par le pointillé peut être une liaison simple ou double ou être absente, auquel cas l'azote est substitué par un hydrogène et R?2¿. X est SO¿2? ou C=O de CH¿2?. Y est -CH(R?4¿)-, -N(R?4¿)- ou -N(R?4¿)-CH¿2?-, O. En outre, R?2¿, R?3¿, R?4¿, R?5¿, R?6¿, R?7¿ et R?8¿ sont conformes à la définition qui en est donnée dans la description. Ces composés conviennent comme modulateurs positifs du récepteur AMPA.
Gouliaev Alex Haahr
Johansen Tina Holm
Larsen Mogens
Mathiesen Claus
Nielsen Elsebet Ostergaard
Mccarthy Tetrault Llp
Neurosearch A/s
LandOfFree
Novel compounds and their use as positive ampa receptor... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Novel compounds and their use as positive ampa receptor..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Novel compounds and their use as positive ampa receptor... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-2012755