Novel compounds for chemiluminescense procedures

Details Novel compounds for chemiluminescense procedures Novel compounds for chemiluminescense procedures

C - Chemistry, Metallurgy

07

D

C07D 417/14 (2006.01) C07D 219/06 (2006.01) C07D 277/62 (2006.01) C07D 401/12 (2006.01) C07D 413/06 (2006.01) C07D 417/04 (2006.01) C12Q 1/28 (2006.01) G01N 21/76 (2006.01) G01N 33/52 (2006.01) G01N 33/533 (2006.01) G01N 33/58 (2006.01)

Patent

CA 2448824

The present invention relates to a chemical compound comprising a light emitting moiety precursor (eg. acridine, luciferine) and a precursor of a leaving group (eg. oxazine, anilide), bound to each other by an amide or by an ester bond and characterized in that the leaving group precursor upon oxidation is converted into the leaving group. The invention also relates to compounds additionally comprising a coupling group to the use of such compounds for labeling of biomolecules and more generally to the use of such compounds in chemiluminescence detection procedures.

La présente invention concerne un composé chimique renfermant un précurseur d'un groupe fonctionnel à émission de lumière et un précurseur d'un groupe partant, liés l'un à l'autre par une liaison d'amide ou d'ester et caractérisés en ce que le précurseur du groupe partant est converti, suite à une oxydation, en groupe partant. Cette invention a également trait à des composés contenant facultativement un groupe de couplage destiné à l'utilisation de tels composés dans l'étiquetage de biomolécules et, plus généralement, à l'utilisation de tels composés dans des procédés de détection de chimioluminescence.

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