Novel compounds for enhancing chemotherapy

Details Novel compounds for enhancing chemotherapy Novel compounds for enhancing chemotherapy

C - Chemistry, Metallurgy

07

D

C07D 241/44 (2006.01) A61K 31/437 (2006.01) A61K 31/497 (2006.01) A61P 35/02 (2006.01) C07D 209/00 (2006.01) C07D 221/00 (2006.01) C07D 401/12 (2006.01) C07D 471/04 (2006.01)

Patent

CA 2404665

The present invention provides chemical compounds, pharmaceutical compositions, and methods for increasing the therapeutic efficacy of drugs. Specifically, the invention provides compounds and compositions for inhibiting drug tranport proteins that efflux therapeutic agents from cells and to methods for using these compounds and pharmaceutical compositions to increase the efficacy of the therapeutic agents that are effluxed by these drug transport proteins.

La présente invention porte sur des composés chimiques, des compositions pharmaceutiques et des procédés visant à accroître l'efficacité thérapeutique des médicaments. L'invention porte notamment sur des composés et des compositions permettant d'inhiber les protéines de transport des médicaments qui écoulent les agents thérapeutiques à partir des cellules, et l'invention porte sur des procédés d'utilisation de ces composés et compositions pharmaceutiques qui confèrent une plus grande efficacité aux agents thérapeutiques qui sont écoulés par les protéines de transport des médicaments.

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