Novel compounds for the management of aging-related and...

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 213/87 (2006.01) A61K 31/4425 (2006.01) A61K 31/4523 (2006.01) A61P 3/10 (2006.01) A61P 9/10 (2006.01) A61P 13/12 (2006.01) A61P 17/00 (2006.01) C07D 213/78 (2006.01) C07D 213/80 (2006.01) C07D 213/82 (2006.01) C07D 401/06 (2006.01) C07D 401/14 (2006.01) C07D 405/06 (2006.01) C07D 405/14 (2006.01) C07D 409/06 (2006.01) C07D 409/14 (2006.01) C07D 417/06 (2006.01)

Patent

CA 2341949

The invention discloses novel compounds of the pyridinium series useful for the management of diabetes and aging-related vascular complications, including kidney disease, nerve damage, atherosclerosis, retinopathy, dermatological disorders and discoloration of teeth, by breaking preformed AGE, or pharmaceutically acceptable salts thereof. The invention also discloses, method for preparation of the novel compounds of the series and pharmaceutical composition comprising one or more of these compounds. The invention further discloses a method of treatment of a diabetic patient by administering the compounds either singly or in combination with drugs for antidiabetic therapy.

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