A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 36/8968 (2006.01) A61K 36/40 (2006.01) A61K 36/428 (2006.01) A61K 36/53 (2006.01) A61K 36/605 (2006.01) A61P 3/10 (2006.01)
Patent
CA 2206012
This invention is directed to a composition effective for the prevention, treatment, and cure of type II diabetes also known as non-insulin-dependent diabetes mellitus. The composition comprises extracts obtained from several medicinal plants proved effective in reducing blood glucose levels in diabetic animals. The possible mechanism of action of the composition involves a combination of increased expression of insulin receptors in hepatocytes and skeletal muscle, increased insulin secretion in pancreatic .beta. cells, an inhibition of .alpha.--glucohydrolase activity, and an increase in the levels of the GLUT (glucose transporter)2 protein in pancreatic B cells. The composition also proved effective in reducing blood glucose levels and restoring the general health of diabetic humans. A preferred composition for the treatment of type II diabetes is comprised of extracts obtained from Orthosiphon aristatus, Cornus officinalis, Trichosanthes kirilowii maxim, Ophiopogon japonicus, and Morus folium.
Jun Hee-Sook
Yoon Ji-Won
Eastwood Biomedical Research Inc.
Gowling Lafleur Henderson Llp
LandOfFree
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