Novel compounds having a guanidine structure and...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 239/42 (2006.01) A61K 31/155 (2006.01) A61K 31/27 (2006.01) A61K 31/415 (2006.01) A61K 31/505 (2006.01) C07C 279/04 (2006.01) C07C 279/08 (2006.01) C07D 233/88 (2006.01) C07D 233/90 (2006.01) C07D 239/22 (2006.01)

Patent

CA 2101058

2101058 9310102 PCTABS00162 La présente invention a pour objet de nouveaux composés à structure guanidique de formule (I), dans laquelle R1 est un radical isopropyle, benzyle éventuellement substitué par un ou plusieurs radicaux (C1-C4) alcoxy ou un radical (a); R2, R3 et R4 sont l'atome d'hydrogène ou ensemble peuvent former un cycle imidazole, pyrimidine, dihydropyrimidine, pyrimidinium. Ces composés sont notamment utiles pour régénérer l'axone des neurones dans certaines maladies comme les neuropathies et myopathies.

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