C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 257/14 (2006.01) A61K 31/155 (2006.01) A61P 31/00 (2006.01) A61P 31/04 (2006.01) A61P 31/10 (2006.01) A61P 31/12 (2006.01) A61P 33/00 (2006.01) C07C 271/16 (2006.01) C07C 277/00 (2006.01) C07C 279/08 (2006.01) C07C 279/12 (2006.01) C07C 279/24 (2006.01)
Patent
CA 2730304
The invention relates to novel compounds having the following formula (I) in which: n is an integer from 1 to 12, in particular from 1 to 8, m and m' are, independently of one another, integers from 0 to 8, - q and q' are, independently of one another, integers from 0 to 2, p and p' are, independently of one another, integers from 0 to 4, A and A' are, independently of one another, a CH2 group, (in the particular case of amidines) an NH group or an NR" group, in which R" is a linear or branched alkyl group containing from 1 to 3 carbon atoms, - B and B' are, independently of one another, an oxygen atom or a CH2 group, and R and R' are, independently of one another, a halogen, such as chlorine, bromine, iodine or fluorine atoms, or a linear or branched alkyl group containing from 1 to 3 carbon atoms, to the use thereof as medicaments and to the method for the preparation thereof.
L'invention concerne de nouveaux composés de formule (I) dans laquelle : n représente un nombre entier compris de 1 à 12, notamment de 1 à 8; m et m' représentent indépendamment l'un de l'autre des nombres entiers de 0 à 8; q et q' représentent indépendamment l'un de l'autre des nombres entiers de 0 à 2; p et p' représentent indépendamment l'un de l'autre des nombres entiers de 0 à 4; A et A' représentent indépendamment l'un de l'autre un groupe CH2, (cas particulier des amidines) un groupe NH ou un groupe NR", dans lequel R" est un groupe alkyle de 1 à 3 atomes de carbone, linéaire ou ramifié; B et B' représentent indépendamment l'un de l'autre un atome d'oxygène ou un groupe CH2; R et R' sont indépendamment l'un de l'autre un halogène, tel que les atomes de chlore, brome, iode ou fluor, ou un groupe alkyle de 1 à 3 atomes de carbone, linéaire ou ramifié, leur utilisation comme médicaments et leur procédé de préparation.
Duval Raphael Emmanuel
Grare Marion
Mourer Maxime
Regnouf-De-Vains Jean-Bernard
Goudreau Gage Dubuc
Universite Henri Poincare - Nancy 1
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