Novel compounds useful in pain management

C - Chemistry – Metallurgy – 07 – C

Patent

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Details

C07C 279/12 (2006.01) A61K 31/155 (2006.01) A61K 31/165 (2006.01) A61K 31/33 (2006.01) A61K 49/00 (2006.01) A61K 51/00 (2006.01) C07C 211/18 (2006.01) C07C 211/27 (2006.01) C07C 233/37 (2006.01) C07C 233/78 (2006.01) C07C 237/22 (2006.01) C07C 237/24 (2006.01) C07C 257/14 (2006.01) C07C 279/24 (2006.01) C07D 213/24 (2006.01) C07D 213/54 (2006.01) C07D 215/12 (2006.01) C07D 307/46 (2006.01) C07D 333/26 (2006.01)

Patent

CA 2335536

Compounds of general formula (I) wherein A is (a) or (b); Z is (CH2)m or a carbonyl group are disclosed and claimed in the present application, as well as their pharmaceutically acceptable salts, pharmaceutical compositions comprising the novel compounds and their use in therapy, in particular in the management of pain. Also intermediates to the compounds of formula (I) are claimed.

L'invention concerne des composés représentés par la formule générale I, dans laquelle A est (a) ou (b); Z est (CH¿2?)¿m? ou un groupe carbonyle; ainsi que des sels pharmaceutiquement acceptables de ceux-ci, des compositions pharmaceutiques renfermant les nouveaux composés et leur utilisation en thérapie, notamment dans le soulagement de la douleur. L'invention concerne également des produits intermédiaires relatifs aux composés représentés par la formule (I).

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