Novel compounds with pharmaceutical properties

Details Novel compounds with pharmaceutical properties Novel compounds with pharmaceutical properties

C - Chemistry, Metallurgy

07

C

C07C 229/46 (2006.01) A61K 31/195 (2006.01) A61K 31/275 (2006.01) A61K 31/335 (2006.01) A61K 31/35 (2006.01) C07C 229/28 (2006.01) C07C 233/53 (2006.01) C07C 255/58 (2006.01) C07C 323/63 (2006.01) C07D 233/78 (2006.01) C07D 241/08 (2006.01) C07D 307/54 (2006.01) C07D 311/90 (2006.01) C07D 333/24 (2006.01) C07D 335/20 (2006.01)

Patent

CA 2234025

A pharmaceutical compound of the formula Image (I) in which R1 is C1-10 alkyl, C2-10 alkenyl, C2-10 alkynyl, C3-10 cycloalkyl, C3-10 cycloalkyl-C1-10 alkyl, C3-10 cycloalkyl-C2-10 alkenyl, C3 10 cycloalky-C2-10 alkynyl, optionally substituted phenyl-C1-10 alkyl, optionally substituted phenyl-C2-10 alkenyl, optionally substituted phenyl-C2-10 alkynyl, optionally substituted naphthyl, optionally substituted naphthyl-C1-10 alkyl, C1-10 alkoxy-C1-10 alkyl, C3-10 cycloalkoxy-C1-10 alkyl, optionally substituted heterocyclyl, optionally substituted heterocyclyl-C1-10 alkyl, optionally substituted phenyl fused to C5-10 cycloalkyl, optionally substituted tricyclic, optionally substituted tricyclic-C1-10 alkyl, or [optionally substituted phenyl(CH2)n]2-C1-10 alkyl, where n is 0 or 1 to 4, and R2 is hydrogen or one of the values for R1; or a salt or ester thereof.

Un composé pharmaceutique possédant la formule Image (I), dans laquelle R1 est un alkyle en C1-10, un alkényle en C2-10, un alkynyle en C2-10, un cycloalkyle en C3-10, un cycloalkyl(en C3-10)-alkyle en C1-10, un cycloalkyl(en C3-10)-alkényle en C2-10, un cycloalkyl(en C3-10)-alkynyle en C2-10, un phénylalkyle en C1-10 facultativement substitué, un phénylalkényle en C2-10 facultativement substitué, un phénylalkynyle en C2-10 facultativement substitué, un naphtyle facultativement substitué, un naphtylalkyle en C1-10 facultativement substitué , un alkoxy(en C1-10)-alkyle en C1-C10, un cycloalkoxy(en C3-10)-alkyle en C1-10, un hétérocyclyle facultativement substitué, un hétérocyclylalkyle en C1-10 facultativement substitué, un phényle condensé sur un cycloalkyle en C5-10 facultativement substitué, un groupe tricyclique facultativement substitué, un groupe tricyclique-alkyle en C1-10 facultativement substitué ou un phényl(CH2)n]2-alkyle en C1-10 facultativement substitué, où n est égal à 0 ou est compris entre 1 et 4 inclusivement et R2 est un hydrogène ou une des valeurs de R1; ou un sel ou un ester de ce composé.

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