Novel coumarin derivatives and the salts thereof, a process...

Details Novel coumarin derivatives and the salts thereof, a process... Novel coumarin derivatives and the salts thereof, a process...

C - Chemistry, Metallurgy

07

D

C07D 311/08 (2006.01) A61K 31/37 (2006.01) A61P 7/00 (2006.01) A61P 39/00 (2006.01) C07D 311/16 (2006.01) C07D 311/18 (2006.01) C07D 498/04 (2006.01) C07H 17/075 (2006.01)

Patent

CA 2417788

The present invention relates to novel coumarin derivatives of formula (I) wherein: X= O or S; n= zero, 1, 2, 3 or 4; R5 and R6, which can be the same or different, are optionally unsaturated C1-C4 alkyl groups, or together with the nitrogen atom they form a residue of cyclic amines optionally containing other heteroatoms; R1= CH3 or phenyl; R2 and R4, which can be the same or different, are H, OH, allyl, halogen or methyl.

La présente invention concerne de nouveaux dérivés de coumarine de formule (I), dans laquelle X représente O ou S; n est égal à zéro, 1, 2, 3, ou 4, R¿5? et R¿6?, qui peuvent être identiques ou différents, sont facultativement des groupes alkyle C¿1?-C¿4? insaturés ou peuvent former avec l'atome d'azote un résidu d'amines cycliques renfermant facultativement d'autres hétéroatomes, R¿1? représente CH¿3? ou le phényle, R¿2? et R¿4, qui peuvent être identiques ou différents, représentent l'hydrogène, OH, un allyle, un halogène ou un méthyle.

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