Novel coumarins, their carboxamide derivatives, preparation...

Details Novel coumarins, their carboxamide derivatives, preparation... Novel coumarins, their carboxamide derivatives, preparation...

C - Chemistry, Metallurgy

07

D

C07D 311/08 (2006.01) A61K 31/37 (2006.01) A61K 31/422 (2006.01) A61K 31/4245 (2006.01) A61K 31/427 (2006.01) A61K 31/4439 (2006.01) A61K 31/465 (2006.01) A61K 31/506 (2006.01) A61P 3/10 (2006.01) A61P 9/10 (2006.01) A61P 9/12 (2006.01) A61P 13/12 (2006.01) A61P 35/00 (2006.01) C07D 311/16 (2006.01) C07D 405/00 (2006.01) C07D 413/00 (2006.01) C07D 413/14 (2006.01) C07D 417/00 (2006.01)

Patent

CA 2508573

This invention discloses a novel coumarin compounds and its amide derivatives, the method for preparing said compounds or the devivatives. The invention also discloses the drug composition comprising said compounds and the devivatives, and the use for especicially kidney protection, treatment for hypertention, cerebrovascular and cardiovascular diseases, diabetes II, tumour, precancerous lesion and dropsy.

L'invention se rapporte à de nouveaux composés de coumarine et à leurs dérivés amides, ainsi qu'au procédé de préparation de ces composants ou de leurs dérivés. L'invention se rapporte également à une composition médicamenteuse comportant ces composés et leurs dérivés ainsi qu'à l'utilisation de cette composition pour protéger particulièrement les reins, pour traiter l'hypertension, les maladies cérébrovasculaires et cardio-vasculaires, le diabète de type II, les tumeurs, les lésions précancéreuses et les hydropsies.

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