Novel crystal form of anhydrous 7-(¬1.alpha., 5.alpha.,...

Details Novel crystal form of anhydrous 7-(¬1.alpha., 5.alpha.,... Novel crystal form of anhydrous 7-(¬1.alpha., 5.alpha.,...

C - Chemistry, Metallurgy

07

D

C07D 471/04 (2006.01) A61K 31/435 (2006.01)

Patent

CA 2223404

The anhydrate of 7-([1.alpha., 5.alpha., 6.alpha.]-6-amino-3- azabicyclo[3.1.0]hex-3-yl)-6-fluoro-1-(2,4-difluorophenyl)-1,4-dihydro-4-oxo- 1,8-naphthyridine-3-carboxylic acid, methanesulfonic acid salt has advantageous stability for formulation as an antibacterial agent.

L'anhydrate de sel d'acide méthane-sulfonique et d'acide 7-([1.alpha., 5.alpha., 6$(a)]-6-amino-3-azabicyclo[3.1.0]hex-3-yl)6-fluoro-1-(2,4-difluorophényl)-1,4-dihydro-4-oxo-1,8-naphtyridine-3 carboxylique possède des propriétés de stabilité avantageuses dans une formulation comme agent antibactérien.

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