Novel crystal forms of ondansetron, processes for their...

Details Novel crystal forms of ondansetron, processes for their... Novel crystal forms of ondansetron, processes for their...

C - Chemistry, Metallurgy

07

D

C07D 401/06 (2006.01) A61K 31/473 (2006.01) C07D 403/06 (2006.01)

Patent

CA 2483532

Ondansetron crystalline Forms A and B are useful in the treatment of nausea and vomiting. Form B has uniquely high melting point of about 244 ~C and both forms are stable against thermally induced polymorphic transition from 30 ~C up to their melting points.

L'invention porte sur des formes cristallines A et B d'ondansetron qui sont utiles dans le traitement de la nausée et des vomissements. La forme B présente un point de fusion exclusivement élevé d'environ 244 ·C et les deux formes sont stables face à la transition à induction thermique de 30 ·C jusqu'à leurs points de fusion.

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