C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 403/06 (2006.01) A61K 31/404 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2734965
The present invention relates to a novel crystalline form of sunitinib free base designated form I and to processes for its preparation. The invention also relates to its use as an API and in the preparation of various forms of sunitinib. Further, the invention relates to pharmaceutical compositions comprising the novel crystalline form and salts, solvates and hydrates prepared according to the invention, and to the uses of said pharmaceutical compositions in the treatment and/or prevention of cancer.
La présente invention concerne une nouvelle forme cristalline de base libre de sunitinib nommée forme I et ses procédés de préparation. Linvention concerne également son utilisation en tant que principe actif et dans la préparation de diverses formes de sunitinib. Linvention concerne également des compositions pharmaceutiques qui comprennent la nouvelle forme cristalline et des sels, solvates et hydrates préparés selon linvention, et les utilisations desdites compositions pharmaceutiques pour le traitement et/ou la prévention du cancer.
Bansode Prakash
Choudhari Bharati
Gore Vinayak
Hublikar Mahesh
Generics [uk] Limited
Osler Hoskin & Harcourt Llp
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