C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 413/12 (2006.01) A61K 31/423 (2006.01) A61P 25/00 (2006.01)
Patent
CA 2750010
The invention relates to novel crystalline hydrate, amorphous and crystalline polymorphic forms of 2-[4-(4-Fluoro- benzyl)-piperidine-1-yl]-2-oxo-N-(2-oxo-2,3-dihydro- benzoxazole-6-yl)- acetamide (I) (radiprodil). Processes for the preparation of these forms, compositions containing these forms, and methods of use thereof are also described.
L'invention porte sur de nouvelles formes cristallines amorphes hydratées et cristallines polymorphes du 2-[4-(4-fluorobenzyl)-pipéridine-1-yl]-2-oxo-N-(2-oxo-2,3-dihydrobenzoxazol-6-yl)-acétamide (I) (radiprodil). L'invention porte également sur des procédés de préparation de ces formes, sur des compositions contenant ces formes et sur des procédés d'utilisation de celles-ci.
Bartane Szalai Gizella
Czibula Laszlo
Demeter Adam
Nemes Andras
Nemet Zoltan
Macrae & Co.
Richter Gedeon Nyrt.
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