C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 233/64 (2006.01) A61K 31/4164 (2006.01) A61P 1/00 (2006.01)
Patent
CA 2695126
The present invention relates to a novel crystal of 5-({[2-amino-3-(4- carbamoyl-2,6-dimethyl-phenyl)-propionyl]- [1-(4-phenyl-Ih-imidazol-2-yl)-ethyl]-amino}-methyl)-2-methoxy-benzoic acid and methods of making the zwitterion of 5-({[2-amino-3-(4-carbamoyl-2,6-dimethyl-phenyl)-propionyl]-[1-(4-phenyl-1h- imidazol-2-yl)-ethyl]-amino}-methyl) -2-methoxy-benzoic acid.
La présente invention concerne de nouveaux cristaux d'acide 5-({[2-amino-3-(4-carbamoyl-2,6-diméthyl-phényl)-propionyl]-[1-(4-phényl-1h-imidazol-2-yl)-éthyl]-amino}-méthyl)-2-méthoxy-benzoïque et des procédés de fabrication du zwitterion de l'acide 5-({[2-amino-3-(4-carbamoyl-2,6-diméthyl-phényl)-propionyl]-[1-(4-phényl-1h-imidazol-2-yl)-éthyl]-amino}-méthyl)-2-méthoxy-benzoïque.
Anzalone Luigi
Fegely Barry
Feibush Penina
Teleha Christopher Allan
Villani Frank J.
Janssen Pharmaceutica N.v.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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