C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 285/36 (2006.01) A61K 31/54 (2006.01) A61K 31/55 (2006.01) C07D 279/02 (2006.01) C07D 417/06 (2006.01) C07D 417/12 (2006.01)
Patent
CA 2319173
The present application describes novel lactams and derivatives thereof of formula (I) or pharmaceutically acceptable salt forms thereof, wherein ring B is a 4-8 membered cyclic sulfonamide containing from 0-3 additional heteroatoms selected from N, O, and S, which are useful as metalloprotease inhibitors.
L'invention concerne de nouveaux lactames, leurs dérivés et leurs sels pharmaceutiquement acceptables, de formule (I), dans laquelle le noyau B est un sulfamide cyclique constitué de 4 à 8 éléments renfermant 0 à 3 hétéroatomes supplémentaires choisis entre N, O et S. Ces composés sont utiles comme inhibiteurs des métalloprotéases.
Chen Lihua
Cherney Robert J.
Decicco Carl P.
Duan Jingwu
Voss Matthew E.
Bristol-Myers Squibb Pharma Company
Dimock Stratton Llp
Dupont Pharmaceuticals Company
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