C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/52 (2006.01) A61K 38/43 (2006.01) C12N 9/00 (2006.01) C12Q 1/25 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2250849
Disclosed are novel human and clam ubiquitin carrier polypeptides involved in the ubiquitination of cyclins A and/or B. Also disclosed are inhibitors of such polypeptides, nucleic acids encoding such polypeptides and inhibitors, antibodies specific for such polypeptides, and methods of their use.
Cette invention concerne de nouveaux polypeptides porteurs d'ubiquitine, lesquels sont d'origine humaine ou proviennent de myes, et jouent un rôle dans l'ubiquitination de cyclines A et/ou B. Cette invention concerne également des inhibiteurs de ces polypeptides, des acides nucléiques codant ces polypeptides et les inhibiteurs, des anticorps spécifiques à ces polypeptides, ainsi que des procédés d'utilisation de ces derniers.
Aristarkhov Alexander
Eytan Esther
Hershko Avram
Kirschner Marc W.
Ruderman Joan V.
President And Fellows Of Harvard College
Rappaport Family Institute For Research In The Medical Sciences
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