C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 317/20 (2006.01) A61K 31/10 (2006.01) A61P 25/28 (2006.01) C07C 317/44 (2006.01) C07D 211/46 (2006.01) C07D 211/60 (2006.01) C07D 211/62 (2006.01) C07D 213/40 (2006.01) C07D 233/56 (2006.01) C07D 295/18 (2006.01) C07D 295/185 (2006.01) C07D 521/00 (2006.01)
Patent
CA 2456420
Novel sulphones of formula I are disclosed: The compounds modulate the processing of amyloid precursor protein by gamma-secretase, and hence are useful in the treatment or prevention of Alzheimer's disease.
L'invention concerne des nouvelles sulfones de formule I. Les composés modulent le traitement de protéine précurseur amyloïde par gamma-sécrétase et sont, par conséquent, utiles dans le traitement ou la prévention de la maladie d'Alzheimer.
Churcher Ian
Dinnell Kevin
Harrison Timothy
Kerrad Sonia
Nadin Alan John
Merck Sharp & Dohme Limited
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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