Novel cyclosporins

Details Novel cyclosporins Novel cyclosporins

C - Chemistry, Metallurgy

07

K

C07K 7/64 (2006.01) A61K 38/13 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2090634

Cyclosporins wherein the residue at the 1-position has the formula I Image in which -x-y- is -CH=CH-(trans) or -CH2-CH2-, X is 0 or S and R is hydrogen, optionally halo or hydroxy substituted- C1-3-alkyl, -alkoxy or -alkylthio, or amino or mono- or di- (C1-2alkyl)-amino, useful as pharmaceuticals, in particular for asthma therapy.

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